// Final-year PhD Candidate · Monash University

Hongxi Yang

I am a final-year PhD candidate in the Department of Data Science and AI, Faculty of IT, Monash University, working in the AIM for Health Lab under the supervision of A/Prof. Zongyuan Ge, Dr. Yasmeen George, and Dr. Deval Mehta. My research focuses on multi-modal deep learning for acute ischemic stroke management, including CT perfusion-based lesion prediction, semantic-guided image synthesis, and interpretable clinical decision support. I also serve as a reviewer for MICCAI.

Hongxi Yang
Bridging AI and Clinical Neuroscience

I am a final-year PhD candidate in the AIM for Health Lab (led by A/Prof. Zongyuan Ge) at Monash University's Faculty of IT. My research sits at the intersection of computer vision, generative AI, and clinical neuroscience.

I play a key technical role in the CRC-P project "AI-powered clinical decision assistance for acute stroke" — a national multi-institution collaboration with Apollo Medical Imaging Technology, Ingham Institute, and Queensland Health. My work spans multi-centre data curation across imaging modalities (CTP, CTA, NCCT) and clinical data, developing end-to-end models for lesion segmentation, large vessel occlusion detection, and treatment outcome prediction, to be validated across 17 hospital sites.

Prior to my PhD, I completed my MSc and BSc at East China Normal University, where I worked on radiomics and deep learning for glioma diagnosis. I also interned at Siemens Healthineers, building cerebral vasculature segmentation and defect inspection systems.

Research Interests

Medical Image Analysis Latent Diffusion Models LLM Fine-Tuning Chain-of-Thought Reasoning Clinical Decision Support Explainable AI Multi-Modal Fusion Stroke Imaging Concept Bottleneck Models

Technical Skills

Python PyTorch MONAI LLaMA-Factory R Linux Git
First-Author Publications
Journal Articles
American Journal of Neuroradiology 2025 · JCR Q1, IF 3.7
Multi-modal CT Perfusion-based Deep Learning for Predicting Stroke Lesion Outcomes in Complete and No Recanalization Scenarios
Hongxi Yang, et al.
Frontiers in Oncology 2022 · JCR Q2, IF 3.3
Radiomics Nomogram Improves the Prediction of Epilepsy in Patients With Gliomas
Jiayi Bai*, Hongxi Yang*, Anqi Gao*, et al. (* co-first author)
Frontiers in Oncology 2021 · JCR Q2, IF 3.3
Radiomics for the Prediction of Epilepsy in Patients With Frontal Glioma
Anqi Gao*, Hongxi Yang*, et al. (* co-first author)
Conference Papers
MICCAI 2026 · Poster
NeRD: Neuro-Symbolic Rule Distillation for Efficient Ontology-Grounded Chain-of-Thought in Medical Image Diagnosis
Hongxi Yang, et al.
IEEE ISBI 2026 · Oral
Semantic-Guided 3D CT Generation for Stroke Lesion Segmentation
Hongxi Yang, et al.
ISMRM 2023 · Oral
Multi-Task Radiomics Approach for Prediction of IDH Mutation Status and Early Recurrence of Gliomas from Preoperative MRI
Hongxi Yang, et al.
ISMRM-ESMRMB 2022 · Oral
Deep Learning Based Automated Diagnosis of Epilepsy in Patients with WHO II–IV Grade Cerebral Gliomas from Multiparametric MRI
Hongxi Yang, et al.
Book Chapter
Springer 2024
Deep Learning: A Primer for Neurosurgeons
Hongxi Yang, et al. — In: Computational Neurosurgery, pp. 39–70.
Research Highlights
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AI-Powered Stroke Decision Support

Key technical contributor to a national CRC-P project with industry and clinical partners. Developed end-to-end pipelines for ischemic lesion segmentation, large vessel occlusion detection, and treatment outcome prediction from multi-modal imaging (CTP, CTA, NCCT) and clinical data — to be validated across 17 hospital sites.

CRC-P Multi-Centre CTP Clinical Deployment
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Semantic-Guided 3D CT Synthesis

Developed a latent diffusion model for synthesizing 3D CT images with controllable stroke lesions. Designed a Spatial-Semantic Feature Interaction Module integrating DINOv2 features with adapters, improving downstream segmentation by up to 22% in Dice.

LDM DINOv2 ControlNet 3D nnU-Net
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Logic-Guided Diagnostic Reasoning

Built an interpretable framework for medical image classification using logic Concept Bottleneck Models to construct Chain-of-Thought reasoning chains, fine-tuning LLMs (Qwen3-VL, LLaVA, LLaMA) via LoRA for clinically grounded diagnosis.

CBM CoT Qwen3-VL LoRA
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Glioma Radiomics & Deep Learning

Developed multi-task radiomics and deep learning models for predicting epilepsy and IDH mutation status in glioma patients from preoperative MRI, with shared feature representations and comprehensive preprocessing pipelines.

Radiomics Multi-Task MRI Glioma
Academic Path
Sep 2023 — Present

PhD in Data Science & Artificial Intelligence

Monash University — Melbourne, Australia
AIM for Health Lab · Supervised by A/Prof. Zongyuan Ge & Dr. Yasmeen George & Dr. Deval Mehta
Sep 2022 — Dec 2022

DTI Intern

Siemens Healthineers Ltd. — Shanghai, China
Cerebral vasculature segmentation from MRI & 3D reconstruction; deep learning-based defect inspection for CT scanner components.
Sep 2020 — Jun 2023

MSc in Radio Physics

East China Normal University — Shanghai, China
Shanghai Key Laboratory of Magnetic Resonance · Supervised by Prof. Guang Yang
Sep 2016 — Jul 2020

BSc in Physics

East China Normal University — Shanghai, China
Get in Touch
✉
Email
hongxi.yang@monash.edu
📍
Location
Melbourne, Victoria, Australia
🏛
Affiliation
AIM for Health Lab, Faculty of IT, Monash University
🎓
Google Scholar

I'm always open to research collaborations, especially in medical AI, multi-modal learning, and stroke neuroimaging. Feel free to reach out if you'd like to discuss ideas or potential projects.

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